Microbiology and Virology
Microbiologia e Virologia
The Laboratory of Microbiology and Virology LMV studies the molecular mechanisms of virus replication and pathogenesis. Our virus model is Human cytomegalovirus (HCMV), the most complex member of Human Herpesviruses family. Research in this field is focused on understanding molecular dynamics of virus-host cell interaction.
In addition, our research is focused on identification and characterization of inhibitors of those molecular mechanisms underlying the activities of selected HCMV proteins, and on development of innovative high-throughput screening assays of candidate new antiviral compounds, or "old" drugs to which we give a "new" life (drug-repurposing).
Another line of research of our laboratory investigates the evolution and diffusion of microorganisms in natural and human-related environments, by taking advantage of classical and the most upfront approaches (e.g. NGS). A particular focus of this line is aimed at improving our understanding the evolution of the budding yeast Saccharomyces cerevisiae and exploring the role of insects in this process.
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