Staff

1. Gribaudo Giorgio (Coordinator)
2. Luganini Anna (Member)
3. Stefanini Irene (Member)
4. Sibille Giulia (Technician)
5. Abba' Silvia (components)
6. Bongiovanni Davide (PhD student)
7. Valentini Beatrice (PhD student)
8. Arianna Maggiora (Student)
9. Pavan Marta (PhD student)
10. Giorgia Cimato (components)
11. Marina Bambi (components)
12. Greta Spagnoli (Student)
13. Francesca Tambasco (Student)
14. Pasquale Toscano (Student)

Contacts

• giorgio.gribaudo@unito.it
• Website
• Send email to members

Activity

The Laboratory of Microbiology and Virology LMV studies the molecular mechanisms of virus replication and pathogenesis. Our virus model is Human cytomegalovirus (HCMV), the most complex member of Human Herpesviruses family. Research in this field is focused on understanding molecular dynamics of virus-host cell interaction.

In addition, our research is focused on identification and characterization of inhibitors of those molecular mechanisms underlying the activities of selected HCMV proteins, and on development of innovative high-throughput screening assays of candidate new antiviral compounds, or "old" drugs to which we give a "new" life (drug-repurposing).

Another line of research of our laboratory investigates the evolution and diffusion of microorganisms in natural and human-related environments, by taking advantage of classical and the most upfront approaches (e.g. NGS). A particular focus of this line is aimed at improving our understanding the evolution of the budding yeast Saccharomyces cerevisiae and exploring the role of insects in this process.

• Discovery and Development on Antiviral Agents
• Microbial evolution and spread
• Virus-host interaction

If it tickles you… then contact us !!!

Our Laboratory offers services, under contracts/conventions, on behalf of public or private entities wishing to perform biological testing on their products or prototypes.

Some of our offerings:

• Cell viability/proliferation and cytotoxicity tests;
• Evaluation of virucidal activity of chemical or naturally occurring solutions;
• Infectivity and viral yield reduction assays of chemical or natural-origin solutions;
• Specific antiviral assays to study the antiviral mechanism of action of the molecule under investigation;
• Evaluation of synergism/antagonism between chemical and/or natural origin solutions;
• Determination of antibacterial activity of pure compounds and mixtures;
• Determination of the minimum concentration inhibiting (MIC) bacterial growth of pure compounds and mixtures;
• Determination of the minimum bactericidal concentration (MBC) of pure compounds and mixtures;
• ASTM E2149 (Standard Test Method for Determining the Antimicrobial Activity of Antimicrobial Agents Under Dynamic Contact Conditions);
• Challenge test aimed at evaluating the effectiveness of the preservative system of a cosmetic productIsolation and identification of microorganisms (bacteria and yeasts);
• Scientific counseling.

Additional antiviral or antimicrobial assays may be requested by the client to meet any specific needs.

For any kind of clarification or to request a quote, please write to the following email addresses:

Prof. Anna Luganini: anna.luganini@unito.it
Dr. Giulia Sibille: giulia.sibille@unito.it
Prof. Irene Stefanini: irene.stefanini@unito.it

Italian version

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